This page is written in the in-universe perspective of the "Garion" series' of novels.

Issus is an one-eyed Nyissan assassin and poisoner. He has a long scar running from his forehead to chin across an empty eye socket. He has at various times been employed by Queen Salmissra, Sadi, and Drasnian Intelligence. He is extremely mercenary as he seems to be primarily motivated by money. He is highly effective at what he does.

In Queen of Sorcery he abducts Garion from Greldik's ship in the harbor of Sthiss Tor and takes him to the Palace. He is equally contemptuous of the eunuchs, guards and snakes he encounters.

In Enchanter's End Game, he poisons Sadi who recovers by taking the antidote which is vile tasting. Sadi, however doesn't bear a grudge and hires Issus to poison the Murgo Ambassador.